Venous Thromboembolic Disease
Codelist metadata
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Coding system
- CTV3 (Read V3)
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Coding system release
- unknown
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Organisation
- OpenSAFELY
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Codelist ID
- opensafely/venous-thromboembolic-disease
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Version Tag
- 2020-09-14
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Version ID
- 237264c7
Versions
About
Description
DEFINITION: A history of venous thromboembolic disease
Variables: (1) a binary variable denoting the presence of one of the codes at any point in the patient record. (2) the earliest date of such a code.
Methodology
Process (1) Read 2 code list from Helen Strongman and Angel Wong combined here: We did not include codes for suspected/possible DVT/PE; nor PEs specified as air embolism or amniotic fluid embolism as would not indicate at ongoing risk of a venous thrombosis/clot. (2) SNOMED searched for DVT and PE
didn't include air embolisms, fat embolisms, or amniotic fluid embolisms or suspected PE assumed unspecified PEs were blood clots. (3) mapped to CTV3 and reviewed by Helen McDonald and Amir Mehrkar, principles discussed with Laurie Tomlinson as above. To reflect the conversation, HM updated the spreadsheet with a final recommendation CTV3venousthromboembolismcombiningcomments.xlsx FLEXIBILITY NEEDED BETWEEN STUDIES: This list
doesn't include fat pulmonary embolism, air pulmonary embolism or amniotic fluid pulmonary embolism (though assumes unspecified PEs are thromboembolic) includes codes for any history of DVT or PE - studies of incident DVT/PE may wish to exclude these. includes codes for PE/DVT in pregnancy, which may not be relevant for all studies includes codes for cerebral venous thrombosis (which may be caused by cerebral inflammation eg. meningitis and is only very rarely associated with PE) and portal thrombosis (which may be caused by liver pathology and should not be able to result in PE) and mesenteric thrombosis, not all of which may be relevant for other study questions. EFFECTS ON COHORT SELECTION: None
POTENTIAL BIASES: This variable includes a history of any venous thrombosis. Some DVTs/PEs will have occurred in the context of a temporary condition (e.g. pregnancy, meningitis, immobility), and some individuals identified by this codelist will be at higher risk of future DVT/PE than others
References
Signed off by
- Helen McDonald, (Sept. 8, 2020)
- Amir Mehrkar, (Sept. 10, 2020)
Codelists are developed by a broad community of users for individual study purposes, which may or may not meet the needs of other studies. They should not be thought of as universal definitions of a particular condition.
We don't offer any guarantees about what they do or don't identify. Users should carefully check that any codelist meets their needs, and seek clinical input where appropriate.
| CTV3Code | CTV3PreferredTermDesc | CTV3Source | Include |
|---|---|---|---|
| 14A8. | H/O: [thrombo-embolism] or [embolism] or [thrombosis] | High_Level_SNOMED | 1 |
| 14A81 | H/O: Deep Vein Thrombosis | CTV3Map_Code_And_Term | 1 |
| 14AC. | H/O: pulmonary embolus | CTV3Map_Code_And_Term | 1 |
| 7A093 | Open pulmonary embolectomy | CTV3Map_Code_And_Term | 1 |
| 7A093 | Open pulmonary embolectomy | CTV3Map_Code_Only | 1 |
| F05.. | Phlebitis and thrombophlebitis of intracranial sinuses | CTV3Map_Code_And_Term | 1 |
| F051. | Cerebral venous sinus thrombosis | CTV3Map_Code_And_Term | 1 |
| F0510 | Cerebral venous thrombosis of cavernous sinus | CTV3_Children | 1 |
| F0511 | Thrombosis of superior longitudinal sinus | CTV3_Children | 1 |
| F0512 | Cerebral venous thrombosis of lateral sinus | CTV3_Children | 1 |
| F0513 | Thrombosis transverse sinus | CTV3_Children | 1 |
| F051z | Thrombosis of central nervous system venous sinus NOS | CTV3Map_Code_And_Term | 1 |
| F053. | Thrombophlebitis of central nervous system venous sinuses | CTV3Map_Code_And_Term | 1 |
| F0530 | Thrombophlebitis of cavernous sinus | CTV3Map_Code_And_Term | 1 |
| F0531 | Thrombophlebitis of superior longitudinal venous sinus | CTV3Map_Code_And_Term | 1 |
| F05z. | Phlebitis or thrombophlebitis of CNS venous sinus NOS | CTV3Map_Code_And_Term | 1 |
| G4010 | Postoperative pulmonary embolus | CTV3Map_Code_And_Term | 1 |
| G676. | Non-pyogenic venous sinus thrombosis | CTV3Map_Code_And_Term | 1 |
| G801. | (Deep vein phlebitis/thrombophleb leg) or (deep vein thromb) | High_Level_SNOMED | 1 |
| G8016 | Thrombophlebitis of the femoral vein | CTV3Map_Code_And_Term | 1 |
| G8017 | Thrombophlebitis of the popliteal vein | CTV3Map_Code_And_Term | 1 |
| G8018 | Thrombophlebitis of the anterior tibial vein | CTV3Map_Code_And_Term | 1 |
| G8019 | Thrombophlebitis of the dorsalis pedis vein | CTV3Map_Code_And_Term | 1 |
| G801A | Thrombophlebitis of the posterior tibial vein | CTV3Map_Code_And_Term | 1 |
| G801B | Deep vein thrombophlebitis of the leg unspecified | CTV3Map_Code_And_Term | 1 |
| G801z | Deep vein phlebitis and thrombophlebitis of the leg NOS | CTV3Map_Code_And_Term | 1 |
| G80y. | (Phleb/thrombophleb iliac vein) or (oth phleb/thrombophleb) | High_Level_SNOMED | 1 |
| G80y4 | Thrombophlebitis of the common iliac vein | CTV3Map_Code_And_Term | 1 |
| G80y5 | Thrombophlebitis of the internal iliac vein | CTV3Map_Code_And_Term | 1 |
| G80y6 | Thrombophlebitis of the external iliac vein | CTV3Map_Code_And_Term | 1 |
| G80y7 | Thrombophlebitis of the iliac vein unspecified | CTV3Map_Code_And_Term | 1 |
| G80y8 | Phlebitis and thrombophlebitis of the iliac vein NOS | CTV3Map_Code_And_Term | 1 |
| G81.. | Portal vein thrombosis | CTV3Map_Code_And_Term | 1 |
| G822. | Embolism and thrombosis of the vena cava | CTV3Map_Code_And_Term | 1 |
| J4202 | Superior mesenteric vein thrombosis | CTV3Map_Code_And_Term | 1 |
| L0964 | Pulmonary embolism following abortive pregnancy | CTV3Map_Code_And_Term | 1 |
| L413. | Antenatal deep vein thrombosis | CTV3_Children | 1 |
| L4130 | Antenatal deep vein thrombosis unspecified | CTV3_Children | 1 |
| L4131 | Antenatal deep vein thrombosis - delivered | CTV3_Children | 1 |
| L4132 | Antenatal deep vein thrombosis with antenatal complication | CTV3_Children | 1 |
| L413z | Antenatal deep vein thrombosis NOS | CTV3_Children | 1 |
| L414. | DVT: [postnatal] or [obstetric phlegmasia alba dolens] | CTV3_Children | 1 |
| L4140 | Postnatal deep vein thrombosis unspecified | CTV3_Children | 1 |
| L4141 | Postnatal deep vein thrombosis - delivered with p/n comp | CTV3_Children | 1 |
| L4142 | Postnatal deep vein thrombosis with postnatal complication | CTV3_Children | 1 |
| L414z | Postnatal deep vein thrombosis NOS | CTV3_Children | 1 |
| L417. | Obstetric cerebral venous thrombosis | CTV3_Children | 1 |
| L4170 | Cerebral venous thrombosis in pregnancy | CTV3_Children | 1 |
| L4171 | Cerebral venous thrombosis in the puerperium | CTV3_Children | 1 |
| L43.. | Obstetric pulmonary embolism | CTV3Map_Code_And_Term | 1 |
| L43.. | Obstetric pulmonary embolism | CTV3Map_Code_Only | 1 |
| L432. | Obstetric blood-clot pulmonary embolism | CTV3Map_Code_And_Term | 1 |
| L4320 | Obstetric blood-clot pulmonary embolism unspecified | CTV3_Children | 1 |
| L4321 | Obstetric blood-clot pulmonary embolism - delivered | CTV3_Children | 1 |
| L4322 | Obstetric blood-clot pulm embolism - delivered with p/n comp | CTV3_Children | 1 |
| L4323 | Obstetric blood-clot pulmonary embolism + a/n complication | CTV3_Children | 1 |
| L4324 | Obstetric blood-clot pulmonary embolism + p/n complication | CTV3_Children | 1 |
| L432z | Obstetric blood-clot pulmonary embolism NOS | CTV3_Children | 1 |
| L43y0 | Other obstetric pulmonary embolism unspecified | CTV3_Children | 1 |
| L43y1 | Other obstetric pulmonary embolism - delivered | CTV3_Children | 1 |
| L43y2 | Other obstetric pulmonary embolism - delivered + p/n comp | CTV3_Children | 1 |
| L43y3 | Other obstetric pulmonary embolism with antenatal comp | CTV3_Children | 1 |
| L43y4 | Other obstetric pulmonary embolism with postnatal comp | CTV3_Children | 1 |
| L43yz | Other obstetric pulmonary embolism NOS | CTV3Map_Code_And_Term | 1 |
| L43z. | Obstetric pulmonary embolism NOS | CTV3Map_Code_And_Term | 1 |
| L43z0 | Obstetric pulmonary embolism NOS, unspecified | CTV3Map_Code_And_Term | 1 |
| L43z1 | Obstetric pulmonary embolism NOS - delivered | CTV3Map_Code_And_Term | 1 |
| L43z2 | Obstetric pulmonary embolism NOS - delivered with p/n comp | CTV3_Children | 1 |
| L43z3 | Obstetric pulmonary embolism NOS with antenatal complication | CTV3_Children | 1 |
| L43z4 | Obstetric pulmonary embolism NOS with postnatal complication | CTV3_Children | 1 |
| Lyu64 | [X]Other obstetric embolism | CTV3_Children | 1 |
| SP122 | Postoperative deep vein thrombosis | CTV3Map_Code_And_Term | 1 |
| X00Dj | Cerebral venous thrombosis of sagittal sinus | CTV3_Children | 1 |
| X00Dk | Cerebral venous thrombosis of straight sinus | CTV3_Children | 1 |
| X00Dl | Cerebral venous thrombosis of sigmoid sinus | CTV3_Children | 1 |
| X00Dm | Cerebral venous thrombosis of cortical vein | CTV3_Children | 1 |
| X012b | Operation for pulmonary embolism | High_Level_SNOMED | 1 |
| X012d | Transluminal fragmentation of pulmonary embolus | High_Level_SNOMED | 1 |
| X202x | Pulmonary thromboembolism | CTV3_Children | 1 |
| X202y | Acute massive pulmonary embolism | CTV3_Children | 1 |
| X202z | Subacute massive pulmonary embolism | CTV3_Children | 1 |
| X205e | Deep thrombophlebitis | High_Level_SNOMED | 1 |
| X205m | Lower venous segment thrombosis | CTV3_Children | 1 |
| X205n | Ileofemoral deep vein thrombosis | CTV3_Children | 1 |
| X76Lg | Phlegmasia alba dolens | CTV3_Children | 1 |
| X76Lh | Phlegmasia caerula dolens | CTV3_Children | 1 |
| XE0Um | Pulmonary embolus | CTV3Map_Code_And_Term | 1 |
| XE0Um | Pulmonary embolus | CTV3Map_Code_Only | 1 |
| XE0VY | Deep vein phlebitis and thrombophlebitis of the leg | CTV3Map_Code_And_Term | 1 |
| XE0VY | Deep vein phlebitis and thrombophlebitis of the leg | CTV3Map_Code_Only | 1 |
| XE0Va | Budd-Chiari syndrome | CTV3Map_Code_And_Term | 1 |
| XE0Va | Budd-Chiari syndrome | CTV3Map_Code_Only | 1 |
| XE0XS | (Deep ven thromb leg)(nonpuer milk-leg)(deep thrombophl leg) | CTV3_Children | 1 |
| XE0q9 | H/O: thromboembolism | High_Level_SNOMED | 1 |
| XE0xL | Postnatal deep vein thrombosis | CTV3_Children | 1 |
| XE0xN | Other obstetric pulmonary embolism | CTV3_Children | 1 |
| Xa07G | Phlebitis and/or thrombophlebitis of iliac vein | CTV3Map_Code_And_Term | 1 |
| Xa1aj | Phlegmasia alba dolens - obstetric | CTV3_Children | 1 |
| Xa1oU | Thrombosis of inferior vena cava | CTV3Map_Code_And_Term | 1 |
| Xa1oV | Thrombosis of superior vena cava | High_Level_SNOMED | 1 |
| Xa6Yr | Axillary vein thrombosis | High_Level_SNOMED | 1 |
| Xa9Bs | Deep vein thrombosis of lower limb | CTV3Map_Code_And_Term | 1 |
| Xa9Bs | Deep vein thrombosis of lower limb | CTV3Map_Code_Only | 1 |
| XaBMc | [V] Personal history deep vein thrombosis | CTV3Map_Code_And_Term | 1 |
| XaBMc | [V] Personal history deep vein thrombosis | CTV3Map_Code_Only | 1 |
| XaBMd | [V] Personal history of pulmonary embolism | CTV3Map_Code_And_Term | 1 |
| XaDyD | Thrombophlebitis of iliac vein | High_Level_SNOMED | 1 |
| XaIIo | Deep vein thrombosis of leg related to air travel | CTV3Map_Code_And_Term | 1 |
| XaJxo | Deep vein thrombosis of leg related to intravenous drug use | CTV3Map_Code_And_Term | 1 |
| XaOYV | Recurrent pulmonary embolism | CTV3Map_Code_And_Term | 1 |
| XaQIV | Deep venous thrombosis of peroneal vein | CTV3Map_Code_And_Term | 1 |
| XaZ43 | Recurrent deep vein thrombosis | CTV3Map_Code_And_Term | 1 |
| XaZHi | H/O venous thromboembolism | High_Level_SNOMED | 1 |
| XaZht | Thrombosis of subclavian vein | High_Level_SNOMED | 1 |
| Xaa2K | Thrombosis of internal jugular vein | High_Level_SNOMED | 1 |
| Xacvd | Unprovoked deep vein thrombosis | CTV3Map_Code_And_Term | 1 |
| Xacve | Provoked deep vein thrombosis | CTV3Map_Code_And_Term | 1 |
Codes not in the full codelist are in faint grey.